Pre-diagnostic carbohydrate intake and treatment failure after radical prostatectomy for early-stage prostate cancer

Radical prostatectomy as treatment for prostate cancer.

Predicting Prostate Cancer Recurrence After Radical Prostatectomy.

BACKGROUND Prostate cancer prognosis is variable, and management decisions involve balancing patients' risks of recurrence and recurrence-free death. Moreover, the roles of body mass index (BMI) and race in risk of recurrence are controversial [1,2]. To address these issues, we developed and cross-validated RAPS (Risks After Prostate Surgery), a personal prediction model for biochemical recurre...

Radical prostatectomy trumps watchful waiting in early prostate cancer. Commentary on: Radical prostatectomy or watchful waiting in early prostate cancer.

BACKGROUND Radical prostatectomy reduces mortality among men with localized prostate cancer; however, important questions regarding long-term benefit remain. METHODS Between 1989 and 1999, we randomly assigned 695 men with early prostate cancer to watchful waiting or radical prostatectomy and followed them through the end of 2012. The primary end points in the Scandinavian Prostate Cancer Gro...

Salvage External Beam Radiotherapy for Prostate Cancer After Radical Prostatectomy

Prostate cancer is the second most common cause of cancer death in American men, with 192,289 new cases and 27,360 deaths expected in 2009.[1] While radical prostatectomy provides excellent control for clinically localized disease, approximately one-third of patients undergoing surgery will have positive surgical margins and another 9% will have seminal vesicle invasion.[2-5] Around one-third o...

Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy.

CONTEXT Salvage radiotherapy may potentially cure patients with disease recurrence after radical prostatectomy, but previous evidence has suggested that it is ineffective in patients at the highest risk of metastatic disease progression. OBJECTIVE To delineate patients who may benefit from salvage radiotherapy for prostate cancer recurrence by identifying variables associated with a durable r...